Single-cell photoacoustic thermometry.
نویسندگان
چکیده
A novel photoacoustic thermometric method is presented for simultaneously imaging cells and sensing their temperature. With three-seconds-per-frame imaging speed, a temperature resolution of 0.2°C was achieved in a photo-thermal cell heating experiment. Compared to other approaches, the photoacoustic thermometric method has the advantage of not requiring custom-developed temperature-sensitive biosensors. This feature should facilitate the conversion of single-cell thermometry into a routine lab tool and make it accessible to a much broader biological research community.
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ورودعنوان ژورنال:
- Journal of biomedical optics
دوره 18 2 شماره
صفحات -
تاریخ انتشار 2013